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Buy Tramadol Online

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Drug Highlights

Generic Name: Tramadol

Brand Name: Ultram, Ultram ER, ConZip, Ryzolt

Classified as: Opioid analgesic

What is Tramadol, and what are the primary uses of it?

Tramadol is a generic version of the brand name Ultram. It is an opioid analgesic for treating moderate to severe pain. The onset of pain relief usually begins within an hour for the immediate-release formulations. Tramadol is available both as a single-ingredient product and in combination with acetaminophen.

Tramadol is a medication that binds the opioid receptors on neurons. It is also an SNRI (serotonin-norepinephrine reuptake inhibitor).


Tramadol is primarily useful in treating both acute and chronic mild to severe pain. The analgesic effects take about 60 minutes to start an action and 2-4 hours to reach the peak concentration for immediate-release formulation. Tramadol has one-tenth potency of morphine on a dose-by-dose basis and almost equally potent to codeine and pethidine.

For moderate pain, Tramadol is equally effective as morphine. The effects of immediate-release Tramadol usually last for six hours after administration.



Chronic pain: an initial dose of 25 mg orally every morning; increase 25 to 50 mg per day at an interval of every three days up to 50 to 100 mg every 4-6 hours. Do not exceed 400 mg a day.

Acute pain: 50 to 100 mg orally every 4-6 hours; Do not exceed 400 mg a day.


Chronic pain: initial dose of 100 mg orally every morning; increase by 100 mg per day every 4-5 days. Do not exceed 300 mg a day.


Do not crush, spilt, or chew the extended-release tablets.

Give a lower dose to the patients of severe renal or hepatic impairment.

It is not recommendable for patients under 17 years of age to take Tramadol.

For the treatment of geriatric patients above 65 years of age, employ a lower dosing regime and give the minimum effective dosages.

How can I take Tramadol, or what precautions should I take during the treatment?

Tramadol is not safe for patients who are allergic to it.

It is essential to get check-ups regularly by the doctor while taking this medication, particularly with the first 24-72 hours following the initiation of treatment.

Never use MAO inhibitors while on the treatment of an opioid such as Tramadol.

Do not take other medicines containing Tramadol as it increases the risks of severe side effects.

Avoid using the medication with alcohol, any alcoholic beverages, or other central nervous system depressants.

Tramadol produces sleep-related breathing problems such as sleep apnea. Immediately consult your doctor if you have any such problem.

Using Tramadol in pregnancy may cause neonatal withdrawal syndrome.

Like other opioids, Tramadol also passes into the breast milk. A nursing mother should avoid taking Tramadol as it can harm the infant.

Seek counsel from a medical professional if you have any severe side effects of Tramadol.

What physical or psychological conditions can affect Tramadol use?

People with the following physical and psychological conditions should not take Tramadol:

  • Decreased adrenal functionality
  • Alcohol withdrawal symptoms, alcoholism, or alcohol intoxication
  • Suicidal behavior or thoughts, depression
  • Serotonin syndrome
  • Asthma or other breathing problems
  • Decreased lung, kidney or liver function
  • Nervous system infection of spinal cord or brain
  • COPD
  • Surgical removal of tonsils or adenoids in pediatric patients
  • Allergy to tramadol or other opioids

Does Tramadol cause side effects, what effects it can include?

The most common Tramadol side effects include dry mouth, nausea, indigestion, dizziness, vomiting, vertigo, constipation, headache, and drowsiness. Constipation and respiratory depression are less severe compared to other opioids.

Central Nervous System

Hallucinations, drowsiness, dizziness, headache, insomnia, agitation, nervousness

Respiratory System

Difficulty breathing

Intestinal Effects

Constipation, diarrhea

Gastric Effects

Nausea, vomiting, heartburn, indigestion

Muscular Effects

Tremor, seizures, weakness, tightness




Sores, swollen tongue or lips, dryness of mouth


Itching, rash, sweating, hives, chills


Sores, swelling




Bruises, swelling, difficulty swallowing, hoarseness

The most severe side effects of Tramadol that needs immediate medical attention include flu-like systematic symptoms, hallucinations, swollen lips or tongue, soreness of nose, throat, or eyes, swelling of hand, feet, eyes, face, or throat, seizures, swallowing problems, hives, and rashes.

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