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What is Chloroquine

Chloroquine is used for malaria. This disease is caused by parasites that enter the body through the bite of a mosquito. This is not effective in all strains of malaria.

Important Information

Chloroquine is a class of drugs known as antimalarials. It works by killing the organisms that cause malaria.

Chloroquine can work to treat rheumatoid arthritis and systemic lupus erythematosus by decreasing the activity of the immune system.

What to know before taking Chloroquine

If you have an allergy reaction to the use of Chloroquine or Chloroquine.

If you use high doses of medication, then it can damage your retina. That damage is irreversible, and this result may cause permanent vision problems. The people who are suffering from the disease like pre-existing eye problems, kidney disease, or the person who is taking tamoxifen.

Before using this medicine, make sure that this medication is safe for you or not. If you have the following, then immediately consult with your doctor;

  • A stomach disorder,
  • Heart disease,
  • Vision changes or damage to your retina that caused by anti-malaria medication,
  • Sugar or diabetes,
  • An allergy to quinine,
  • Habit or addiction to alcohol,
  • Liver or kidney disease,
  • A disease that affects your skin or your nervous system,
  • A genetic enzyme deficiency is known as glucose-6 phosphate dehydrogenase deficiency.

Contact your doctor if you are pregnant or if you are going to be pregnant. This disease, malaria, can cause severe illness or death in pregnant women.

Malaria can also increase miscarriage, premature delivery, low birth weight, or stillbirth during the pregnancy.

It does not confirm that this chloroquine is harmful to the unborn baby or not. Do not travel in an area where the disease malaria is common. If you want to travel to that place, ask your doctor about the risk of traveling areas and take precautions—the area where this disease is common like Africa, South America, and southern Asia.

 

This medication is not allowed to the person or children younger than 18 years old or for treatment for lupus or rheumatoid arthritis in any person younger than 18 years old.

If you are a mother and breastfeed children during this medicine, before it consults with your doctor, take precautions or know all the risks.

How to take Chloroquine

Read and follow all the instructions that instruct on the prescription label.

Use this medicine with the food, or you can take it with a glass of milk unless your doctor told you.

If you want to prevent malaria, use this medicine a week before entering an area where malaria is common.

Continue this medicine at least for 28 days after leaving the area.

Use this medication mainly given as one high dose followed by smaller doses while taking the next two days in a row.

 

It is not sure that every medicine is working to cure all strains of malaria. No medication is 100% effective in the treatment of malaria.

Consult with your doctor if you have vomiting or diarrhea during your treatment.

Chloroquine Dosage

Concomitant medication with an 8-aminoquinoline compound is necessary to treat the hypnozoite liver stage forms of Plasmodium vivax and P ovale.

 

For the treatment of uncomplicated malaria due to susceptible strains of P falciparum, P malariae, P-value, and P vivax

 

US CDC Recommendations: 600 mg base (1 g salt) orally at once, followed by 300 mg base (500 mg salt) orally at 6, 24, and 48 hours

Total dose: 1.5 g base (2.5 g salt)

 

Comments:

-Recommended for uncomplicated malaria in regions with chloroquine sensitivity

-Recommended for uncomplicated malaria in all regions; if treating P vivax or P ovale infections, concomitant treatment with primaquine or tafenoquine is recommended.

-Recommended for malaria treatment for pregnant women in regions with chloroquine sensitivity

-Pregnant patients with infections should receive chloroquine prophylaxis during pregnancy; after delivery, patients with regular G6PD activity should be treated with primaquine or tafenoquine or continue chloroquine prophylaxis for one year.

-Current guidelines must be consulted for additional information.

Usual Adult Dose for Amebiasis

1 g salt orally once a day for two days, followed by 500 mg salt once a day for at least 2 to 3 weeks

 

Comments:

-Treatment is usually combined with an effective intestinal amebicide.

 

Use: For the treatment of extraintestinal amebiasis

 

Overdose

who can treat the overdose of this medicine immediately?

If an overdose occurs then you have a symptom like;

  • Slow heart rate,
  • Sudden dizziness,
  • Shortness of breathing,
  • Or slow breathing,
  • Fainting,
  • Weak pulse,

 

Do not allow this medication to give to children. Would you mind keeping it away from children?

 

What to avoid while using Chloroquine

Do not take an antacid or Kaopectate within 4 hours or before 4 hours after you take Chloroquine.

 

This medication can cause blurred vision or blindness

Do not drink alcohol while taking this medicine, and when this medicine starts working on your body, do not drive or don’t do any harmful activity.

Chloroquine Side Effects

If you were suffering from an allergic reaction to this medication, then you have the symptoms like

  • Serious skin reaction,
  • Burning eyes,
  • low blood sugar-headache
  • Red or purple skin rash,
  • The problem in breathing,
  • Swelling on your face or throat.

 

If you have a side effect, then consult with your doctor if you have the symptoms like;

  • Sudden dizziness,
  • The problem in breathing,
  • Fluttering in the chest,
  • Pounding heartbeats

 

Immediate Consult with your doctor if you have:

  • Ringing in your ear, difficulties in hearing,
  • Unusual mood change or behavior,
  • Yellowish of your eyes,
  • Serious muscle weakness,
  • Low blood cell counts,
  • Low blood sugar,
  • A severe drug interaction that can affect many parts of your body

 

Common Side Effects;

  • Headache, dizziness,
  • vomiting, diarrhea
  • unusual change in mood
  • Hair loss,
  • Vomiting, stomach pain,

 

Immediately stop your medicine on behalf of doctor suggestion and say to your doctor if you have;

  • Change in color vision,
  • Hazy or cloudy vision,
  • Increased sensitivity to light.
  • Blindspot
  • Problem in focusing

What drug can interact with Chloroquine

Chloroquine can cause serious heart problems. Maybe you have a higher risk if you use specific medicine for infections, asthma, heart problems, high blood pressure, depression, cancer, HIV.

If you take an antibiotic like ampicillin, take it one hour or 2 hours before using the Chloroquine dose.

Say to your doctor if you use medicine mainly;

  • Praziquantel,
  • Tamoxifen,
  • Insulin,
  • Cimetidine,
  • Mefloquine,

 

 

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